She died in a helicopter air ambulance on the way to Santa Rosa Memorial Hospital, the CHP said.
Ms. Woodrow, alone in a 2003 Honda CRV, was headed south on 101 at a speed of 50 to 55 mph. At around 5:30 p.m. near Old Sherwood Road she apparently crossed the double yellow lines into the northbound lane and collided with a 1997 Toyota T100 pickup truck occupied by Berkeley residents Paul Webb, 58, and Monica Winu, age unknown, the CHP said.
Both Mr. Webb, who was driving, and Ms. Winu suffered major injuries, the CHP said. Mr. Webb was taken by ground to Howard Hospital in the city of Willits and Ms. Winu was flown to Santa Rosa Memorial.
Investigators are looking into the cause of the accident.
Medics found the two vehicles blocking both lanes and had to extricate Ms. Woodrow from her car, the CHP said.