Menlo-Atherton batters struck out 15 times during the Bears' loss to visiting Woodside.
M-A (1-2, 4-9-1) managed just two ground outs and a pop-up in foul territory.
It was a six-inning game, so of the 18 outs, all but three were strikeouts by the right-handed Patton, a junior at Woodside High.
The Woodside Wildcats now have a record of 11-4-1 overall and 2-0 in the PAL Ocean Division.
Patton has a record of 10-4-1 and pitched a 7-inning no-hitter earlier this season against Watsonville, said Coach Mike King, who is in his 10th season at Woodside High.
At the plate, Patton batted 2 for 4, including a double, in the April 2 contest. Second baseman Rebecca Pilakowski fielded a tough ground ball to help preserve the perfect game.