Yuan, whose family opened the Chinese restaurant at 4880 El Camino Real in 1990, said she and her husband Carson were ready to retire after 25 years. They recently sold the property, she said.
"We can't fully express our deep gratitude for your business and support," a message announcing the closure on the restaurant's website reads. "Having had the opportunity to serve you has been nothing but an absolutely pleasure."
The Yuan family, who is originally from Taiwan, opened the first Hunan Home's in San Francisco's Chinatown in 1983. Yuan said that restaurant is still in operation.
Carson Yuan, owner of Hunan Home's Restaurant in Los Altos, prepares a meal inside the kitchen in 2006. Palo Alto Weekly file photo.
Last year, a younger member of the family, Jarvis Yuan, took over another local Chinese restaurant: Hunan Garden in Palo Alto, previously owned by his father, Simon Yuan. He reopened the longtime restaurant as Mandarin Roots in May 2014.